Condition

COPD is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute to the overall severity in individual patients. The condition is non reversible and can become more serious over time.

Individual at risk

Donor

Guidance at RECRUITMENT

UNACCEPTABLE

Proposed guidance at CT/WORK-UP

May be acceptable for PBSC only if mild disease (equivalent to GOLD I-II, FEV1>50%).

Justification for guidance

General anesthesia induces a significantly increased risk for postoperative pulmonary morbidity.

References

http://www.who.int/mediacentre/factsheets/fs315/en/index.html

Global Initiative for Chronic Obstructive Lung Diseases Pocket Guide to COPD Diagnosis, Management, And Prevention, 2013 (http://www.goldcopd.org)

Notes

Included in ICD-9 codes 490-496