Condition

Household contact of person with hepatitis B infection

Individual at risk

Recipient

Guidance at RECRUITMENT for adult volunteer donor and maternal donor (cord blood donation)

Acceptable if donor can prove to be hepatitis B surface antibody positive.

Guidance at CT/WORK-UP

Donor may be accepted only if:

Donor is negative for all markers

OR

Donor is hep B core antibody positive, heb B surface antigen negative and hep B surface antibody has been documented to be more than 100 iu/l at some time.

Justification for GUIDANCE

Hepatitis B infection can be passed to close household contacts and might be passed on to recipient by transplant of stem cells.

Notes

This advice is a requirement of the EU Tissues and Cells Directive.