Condition
Atherosclerotic or thrombotic occlusion of the coronary vasculature.
Pseudonyms and other related conditions include:
Angina
Ischaemic heart disease (IHD)
Myocardial infarction (MI)
Heart attack
Guidance at RECRUITMENT for adult volunteer donor (NA for maternal donor (cord blood donation))
UNACCEPTABLE
Guidance at CT/WORK-UP
UNACCEPTABLE, PERMANENT DEFERRAL
Individual at Risk
Donor
Justification
Myocardial infarction and angina have been well-documented as complications of both bone marrow and mobilised stem cell collection. In donors with known coronary artery disease, both processes pose an unacceptable risk to donor.
References
Halter J, Kodera Y, Ispizua AU, Greinix HT, Schmitz N, Favre G et al. Severe events in donors after allogeneic hematopoietic stem cell donation. Haematologica 2009; 94(1): 94-101.