Condition
Hereditary elliptocytosis (HE) aka hereditary ovalocytosis, is a heterogeneous group of inherited red blood cell (RBC) disorders characterized by elongated, oval, or elliptically shaped RBCs on peripheral blood smear. Hemolytic anemia in these disorders can range from absent to life-threatening.
Guidance at RECRUITMENT
ACCEPTABLE
Guidance at CT/WORK-UP
Accept, if no clinically significant hemolysis, at the discretion of transplant center.
Unacceptable if active hemolysis.
Justification for guidance
Hemolytic anemia poses risk to both donor and recipient. If no evidence of hemolysis, inform transplant center of diagnosis and proceed if TC prefers. Donor must not donate if clinically significant hemolysis.
References
Donor suitability working group WMDA meeting Hanau 2023.
Kalfa, T., Takemoto, C., & Tirnauer, J. (2023). Hereditary elliptocytosis and related disorders. UpToDate. Retrieved October 10, 2023 from