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A patient registration embedded block is sent together with each request. This block contains both wmdaId and patientId of the patient.
- Next to the actual request information, whenever the institutions are needed, they are sent explicitly as an Embedded Address Block.
The requested donor has to be reserved at the remote hub and reported back to the requesting registry by an embedded donor block with the donor status reflecting the change (a.k.a. DONOR_CB with D_STATUS = ”RS”).
- All changes in the donors (change of status, updated typing or IDMs) resulting from the requests are reported back in an embedded donor block. A separate update must be made to the Search & Match system with the updated donor data to ensure up-to-date master data. More information on how to do so may be found here.
- ReferenceCode: In order to couple messages to the same request, e.g. Sample Request and its results, all messages following the initial request must have a referenceCode as part of the message.
- Each field inherited from EMDIS Semantics contains a comment describing its purpose in EMDIS and its original name to assist in transition from EMDIS to Match-Connect.
- Paragraph Request + Response Flows depicts the new message flows.
5.1 - Extended Typing Request (TYP_REQ)
This message is used to request an extended typing of a donor (adult, ADCU, CBU). It primarily contains information about what to type and for which donor.
Expected return message is Extended Typing Results or Request Rejected.
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The appropriate action if the typing request cannot be accepted or has to be changed by the recipient, e.g. due to national rules, is to inform the requesting side what was done. If only the resolution was changed (the sender will receive something different than ordered - either more or less) or only a part of the requested loci were accepted (the sender will only receive parts of what was ordered): send a MSG_RSP containing the warning.
5.2 - Extended Typing Results (TYP_RES)
This message is used to send the results of the Extended Typing Request back to the requesting registry.
| Send | Retrieve |
| extendedTypingResponseRequest | extendedTypingResponseRetrieve |
| Expand |
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| | Field | Details |
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| response | | Expand |
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| | Field | Details |
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| referenceCode | string($uuid) | | hlaNomenclatureVersion | string default: 3Major version of HLA Nomenclature HLA_NOM_VER Req 7 | | etSampleType | string nullable: trueType of sample. AS = CBU Contiguous Attached Segment WB = Whole Blood Sample RC = Red Cell Fraction (pellet) FP = Blood Spotted Filter Paper ED = Extracted DNA Enum: Array [ 5 ] | | remark | string maxLength: 120 nullable: true example: patient case is very urgentRemark REMARK Opt 120 |
|
| | recipient | integer maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | donor | Embedded Donor Block | | patient | Patient ID |
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| | Expand |
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| | No parameters specified |
|
...}| metaInformation | Embedded Meta Block |
Rules
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5.3 - Sample Request (SMP_REQ)
This message is used to request a VT (verification typing) of a specific donor/product for a patient.
| Send | Retrieve |
|---|
| sampleRequestRequest (comments refer to changes to the current API definition) | sampleRequestRetrieve |
| Expand |
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| | Field | Details |
|---|
| request | | Expand |
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| | requestDate | string($date-time) Request date REQ_DATE Req 8 yyyy-MM-dd [or yyyyMMdd] | | prod1 | {...} | | prod2 | {...} | | prod3 | {...} | | prod4 | {...} | | earliestDateCanReceive | string($date-time) Earliest date of sample reception REC_DATE1 Req 8 yyyy-MM-dd [or yyyyMMdd] | | latestDateCanReceive | string($date-time) nullable: trueLatest date of sample reception REC_DATE2 Opt 8 yyyy-MM-dd [or yyyyMMdd] | | acceptableReceptionDaysOfWeek | integer nullable: true minLength: 7 maxLength: 7 example: 1111100Weekdays acceptable for reception. Binary fixed length string for the 7 days in the week. E.g., 1110000 means acceptable days for reception are Monday, Tuesday and Wednesday, not acceptable days are Thursday, Friday, Saturday or Sunday. | | institutionToSendSampleTo | Embedded Address Block | | institutionPaying | Embedded Address Block | | urgent | boolean Urgent request URGENT Opt 1 | | acknowledgementId | string maxLength: 17 nullable: true example: 1234567890abcdefgAcknowledgement ID ACK_ID Opt 17 | | remark | string maxLength: 120 nullable: true example: patient case is very urgentRemark REMARK Opt 120 |
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| | recipient | integer maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | patient* | Embedded Patient Block | | donor* | Donor ID |
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| | Expand |
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| No parameters specified |
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Rules:
The fields ”earliest and latest date of sample reception” represent the lower and upper limit of a period of time in which the blood sample has to be received. If the second date is missing the sample may be received any time after the first date.
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If the number of tubes is unassigned, not given in the request, the default value number of tubes is one.
This message is used to send relevant secondary information which may arise in the context of sample request.
| Send | Retrieve |
| sampleInfoRequest (comments refer to changes to the current API definition) | sampleInfoRetrieve |
| Expand |
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| | referenceCode* | string($uuid) | | informationType* | string maxLength: 3 minLength: 3Information Type INFO_TYPE Req 3 Enum: Array [ 12 ] | | remark | string nullable: trueRemark REMARK Opt 120 | | recipient | integer maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | patient* | Patient ID | | donor* | Embedded Donor Block |
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| | Expand |
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| | No parameters specified |
|
Rules:
The message can only be exchanged in one direction: from donor side to patient side.
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There might be several sample information messages within the context of one sample request. Subsequent sample information is regarded as new or additional information and not as updates.
5.5 - Sample Arrival (SMP_ARR)
This message is used to transmit the proposed date of the sample arrival.
| Send | Retrieve |
| sampleArrivalRequest (comments refer to changes to the current API definition) | sampleArrivalRetrieve |
| Expand |
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| | Field | Details | | message | | Expand |
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| | Field | Details |
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| referenceCode* | string($uuid) | | arrivalDate* | string($date-time) Proposed date of sample arrival ARRV_DATE Req 8 | | collectionDate | string($date-time) nullable: trueDonor blood collection date COLL_DATE Opt 8 | | labelId* | string maxLength: 19Verbatim verification typing (VT) sample label ID D_LABEL_ID Req 19 | | etSampleType | string nullable: trueType of sample. AS = CBU Contiguous Attached Segment WB = Whole Blood Sample RC = Red Cell Fraction (pellet) FP = Blood Spotted Filter Paper ED = Extracted DNA Enum: Array [ 5 ] | | remark | string maxLength: 120 nullable: true example: patient case is very urgentRemark REMARK Opt 120 |
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| | recipient | integer maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | patient* | Patient ID | | donor* | Embedded Donor Block |
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| | Expand |
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| | No parameters specified |
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5.6 - Sample Results (SMP_RES)
This message is used to transmit the results of the sample testing.
| Send | Retrieve |
| sampleResponseRequest (comments refer to changes to the current API definition) | sampleResponseRetrieve |
| Expand |
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| | Field | Details |
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| response | | Expand |
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| | Field | Details |
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| referenceCode* | string($uuid) | | hlaNomenclatureVersion* | string default: 3Major version of HLA Nomenclature HLA_NOM_VER Req 7 | | hla | {...} | | idm | {...} | | abo | string nullable: trueEnum: Array [ 4 ] | | rhesus | string nullable: trueEnum: Array [ 2 ] | | donorStillOfInterest | string maxLength: 1Donor still of interest DON_ACCPT Req 1 Enum: Array [ 2 ] |
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| | recipient | integer maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | patient* | Patient ID | | donor* | Donor ID |
|
| | Expand |
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| | No parameters specified |
|
Rules:
donorStillOfInterest = ”N” means: donor can be released immediately.
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If Sample Results cannot be sent then a Request Rejected message should be sent with the reason field populated to explain why.
5.7 - Infectious Disease Marker Request (IDM_REQ)
This message is used to request infectious disease marker test results of the selected donor.
| Send | Retrieve |
| infectiousDiseaseMarkerRequest | infectiousDiseaseMarkerRequestRetrieve |
| Expand |
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| | Field | Details |
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| referenceCode* | string($uuid) | | markerAsArray | [...] | | marker* | integer maxLength: 19 minLength: 19 example: 111110000111Binary fixed length string in which each position represents a test to be requested: details in Data Dictionary | | institutionPaying* | Embedded Address Block | | acknowledgementId | string maxLength: 17 nullable: true example: 1234567890abcdefgAcknowledgement ID ACK_ID Opt 17 | | remark | string maxLength: 120 nullable: true example: Please also test for SARS-CoV-2Remark REMARK Opt 120 | | recipient* | integer maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | patient* | Embedded Patient Block | | donor* | Donor ID |
|
| | Expand |
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| | No parameters specified |
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Rules:
Several distinct requests for the same patient / donor pair at a time are possible, for example, a verification typing and a CMV status, but each request has to be answered by an individual IDM Results, i.e. results must not be ”concatenated” to a single result message. Multiple IDM
requests for the same patient / donor pair have to be disjoint (i.e. may not contain identical markers). The occurrence of multiple requests should be an exception. Normally, all markers required should be requested within one message.
5.8 - Infectious Disease Marker Results (IDM_RES)
This message is used to send the results of the IDM request back to the requesting registry.
| Send | Retrieve |
| infectiousDiseaseMarkerResultRequest | infectiousDiseaseMarkerResultRetrieve |
| Expand |
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| | Field | Details |
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| referenceCode* | string($uuid) | | markerAsArray | [...] | | marker | integer maxLength: 19 minLength: 19 example: 111110000111Binary fixed length string in which each position represents a test to be requested: details are in Data Dictionary | | sampleExtractionDate | string($date-time) nullable: trueDate of sample extraction D_EXTR_DATE Opt 8 | | donorCcr5Status | string maxLength: 2 nullable: trueDonor CCR5 status D_CCR5 Opt 2 | | donorWeightKg | integer($int32) maximum: 999 minimum: 0 nullable: trueDonor weight in kilograms D_WEIGHT Opt 3 | | donorHeightCm | integer($int32) maximum: 999 minimum: 0 nullable: true example: 175Donor height in centimetres D_HEIGHT Opt 3 | | numberOfTransfusions | integer($int32) maximum: 9 minimum: 0 nullable: trueNumber of transfusions D_NMBR_TRANS Opt 1 | | numberOfPregnancies | integer($int32) maximum: 9 minimum: 0 nullable: trueNumber of pregnancies D_NMBR_PREG Opt 1 | | idm | {...} | | remark | string maxLength: 120 nullable: trueRemark REMARK Opt 120 | | recipient | integer maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | donor* | Embedded Donor Block | | patient* | Patient ID |
|
| | Expand |
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| | No parameters specified |
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Rules
The common use of IDM Results message is in response to Sample Request message, in addition to shipment of the donor blood sample. Please note there may be charge involved with this service. If a fee is charged, it may come as a separate item or might be included in the price of the sample shipment. Such IDM Results messages can be sent via a regular EMDIS message - the remote hub must be able to handle it appropriately. The IDM Results must have the same referenceCode as the Sample Request message.
IDM Results message can be generated in response to two different message requests:
1. Sample Request does not specify what set of infectious disease markers to be tested
2. IDM Request does specify what set of infectious disease markers to be tested
The field marker is a required field.
For those hubs reporting infectious disease markers during verification typing, the marker field should contain the IDMs actually tested. There is a fixed length binary field for the IDM Results message. The blood group may be also reported.
IDM results can be also reported as a part of Sample Results message by the hub (transplant center) that requested the blood sample. This is to give the transplant centers the possibility to report the results of IDMs they might have tested.
5.9 - Reservation Request (RSV_REQ)
This message is used to request the reservation of a donor for transplant at the receiving registry.
| Send | Retrieve |
| reservationRequestRequest | reservationRequestRetrieve |
| Expand |
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| | Field | Details |
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| payload* | | Expand |
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| | Field | Details |
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| patient* | Embedded Patient Block | | donor | Donor ID | | requestDate* | string($date-time) Request date REQ_DATE Req 8 yyyy-MM-dd [or yyyyMMdd] | | referenceCode* | string($uuid) | | expirationDate | string($date-time) nullable: trueRequest date EXPI_DATE Opt 8 yyyy-MM-dd [or yyyyMMdd] | | acknowledgementId | string maxLength: 17 nullable: true example: 1234567890abcdefgAcknowledgement ID ACK_ID Opt 17 | | remark | string maxLength: 120 nullable: trueRemark REMARK Opt 120 |
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| | recipient* | string maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | correlationGuid* | string($uuid) Sender generated GUID used to correlate response acknowledgement |
|
| | Expand |
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| | No parameters specified |
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5.10 - Reservation
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Result (RSV_RES)
This message is used to notify the requesting patient registry if the Reservation Request has been confirmed by the donor registry.
| Send | Retrieve |
| reservationResponseRequest | reservationResponseRetrieve |
| Expand |
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| | Field | Details |
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| sender* | string maxLength: 4 minLength: 4 example: 56784 digit ION of sender | | sentAtUtc* | string($date-time) Server-supplied timestamp showing UTC time sender posted (i.e. sent) MessageRequest. | | deliveredAtUtc* | string($date-time) Server-supplied timestamp showing UTC time of Message delivery to recipient's inbox queue. | | payload* | | Expand |
|---|
| | Field | Details |
|---|
| patient* | Patient ID | | donor* | Embedded Donor Block | | referenceCode* | string($uuid) | | expirationDate | string($date-time) nullable: trueDate expiration of reservation EXPI_DATE Opt 8 yyyy-MM-dd [or yyyyMMdd] | | confirmed* | boolean Confirmation of reservation CONFIRM Req 1 | | remark | string maxLength: 120 nullable: trueRemark REMARK Opt 120 |
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| | recipient* | string maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | correlationGuid* | string($uuid) Sender generated GUID used to correlate response acknowledgement | | messageType | string Message types supported by WmdaConnect Enum: Array [ 21 ] |
|
| | Expand |
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| | No parameters specified |
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5.11 - Donor Release Request (
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new message)
This message is sent by the patient registry to inform the donor registry that a donor can be released from the reservation when it is no longer needed (e.g. patient deceased or was transplanted with another donor). This should be used if the donor reservation was confirmed in a response to some request. If the reservation has not been confirmed then a Request Cancellation message should be used.
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There is no response to this message except for the automated acknowledgement.
| Send | Retrieve |
| reservationReleaseRequest | reservationReleaseRetrieve |
| Expand |
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| | Field | Details |
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| sender* | string maxLength: 4 minLength: 4 example: 56784 digit ION of sender | | sentAtUtc* | string($date-time) Server-supplied timestamp showing UTC time sender posted (i.e. sent) MessageRequest. | | deliveredAtUtc* | string($date-time) Server-supplied timestamp showing UTC time of Message delivery to recipient's inbox queue. | | payload* | | Expand |
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| | Field | Details |
|---|
| patient* | Patient ID | | donor* | Donor ID | | referenceCode* | string($uuid) | | requestType* | string maxLength: 3Type of request REQ_TYPE Req 3 | | reason | string maxLength: 3 minLength: 3 nullable: trueReason of request cancellation REASON_CNCL Opt 3 | | remark | string maxLength: 120 nullable: trueRemark REMARK Opt 120 |
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| | recipient* | string maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | correlationGuid* | string($uuid) Sender generated GUID used to correlate response acknowledgement | | messageType | string Message types supported by WmdaConnect Enum: Array [ 21 ] |
|
| | Expand |
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| | No parameters specified |
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5.12 - Workup Request
Future Phase
5.13 - Workup Status
Future Phase
5.14 - Request Cancellation (REQ_CAN)
This message is used to cancel a previous request that has been sent to the donor registry. The Request must have a preceding request that is being cancelled.
| Send | Retrieve |
| requestCancellationRequest | requestCancellationRetrieve |
| Expand |
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| | Field | Details |
|---|
| sender* | string maxLength: 4 minLength: 4 example: 56784 digit ION of sender | | sentAtUtc* | string($date-time) Server-supplied timestamp showing UTC time sender posted (i.e. sent) MessageRequest. | | deliveredAtUtc* | string($date-time) Server-supplied timestamp showing UTC time of Message delivery to recipient's inbox queue. | | payload* | | Expand |
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| | Field | Details |
|---|
| patient* | Patient ID | | donor* | Donor ID | | referenceCode* | string($uuid) | | requestType* | string maxLength: 3Type of request REQ_TYPE Req 3 | | reason | string maxLength: 3 minLength: 3 nullable: trueReason of request cancellation REASON_CNCL Opt 3 | | remark | string maxLength: 120 nullable: trueRemark REMARK Opt 120 |
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| | recipient* | string maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | correlationGuid* | string($uuid) Sender generated GUID used to correlate response acknowledgement | | messageType | string Message types supported by WmdaConnect Enum: Array [ 21 ] |
|
| | Expand |
|---|
| | No parameters specified |
|
5.15 - Request
...
Rejected (NO_RES)
This message is used to notify the requesting registry when a request cannot be fulfilled (service cannot be provided).
| Send | Retrieve |
| requestRejectedRequest | requestRejectedRetrieve |
| Expand |
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| | Field | Details |
|---|
| payload* | | Expand |
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| | Field | Details |
|---|
| patient* | Patient ID | | donor* | Embedded Donor Block | | referenceCode* | string($uuid) | | requestType* | string maxLength: 3Type of request REQ_TYPE Req 3 | | reason* | string maxLength: 3 minLength: 2Reason REASON Req 3 | | remark | string maxLength: 120 nullable: trueRemark REMARK Opt 120 |
|
| | recipient* | string maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | correlationGuid* | string($uuid) Sender generated GUID used to correlate response acknowledgement |
|
| | Expand |
|---|
| | No parameters specified |
|
5.16 - Result Reminder (RES_REM)
This message is sent by the requesting registry to the receiving registry to remind the receiving registry of an outstanding result from a previous request.
| Send | Retrieve |
| resultReminderRequest | resultReminderRetrieve |
| Expand |
|---|
| | Field | Details |
|---|
| sender* | string maxLength: 4 minLength: 4 example: 56784 digit ION of sender | | sentAtUtc* | string($date-time) Server-supplied timestamp showing UTC time sender posted (i.e. sent) MessageRequest. | | deliveredAtUtc* | string($date-time) Server-supplied timestamp showing UTC time of Message delivery to recipient's inbox queue. | | payload* | | Expand |
|---|
| | Field | Details |
|---|
| patient | Patient ID | | donor | Donor ID | | requestDate | string($date-time) nullable: trueRequest date REQ_DATE Opt 8 yyyy-MM-dd [or yyyyMMdd] | | referenceCode* | string($uuid) | | resultType* | string maxLength: 9Type of result reminded RES_TYPE Req 9 | | expirationDate | string($date-time) nullable: trueRequest date EXPI_DATE Opt 8 yyyy-MM-dd [or yyyyMMdd] | | remark | string maxLength: 120 nullable: trueRemark REMARK Opt 120 |
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| | recipient* | string maximum: 9999 minimum: 0 maxLength: 4 minLength: 4 example: 12344 digit ION of recipient | | correlationGuid* | string($uuid) Sender generated GUID used to correlate response acknowledgement | | messageType | string Message types supported by WmdaConnect Enum: Array [ 21 ] |
|
| | Expand |
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| | No parameters specified |
|
5.17 - Generic Request (new message)
This message is used for registering a patient (by the embedded patient block).
This may be required for example for direct WU requests until 5.11 is available or to reactivate a closed patient case on receiving registry side.
5.18 Request + Response Flows
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