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titleInformation for healthcare professionals:

Table of Contents

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titleImportant webpages:
Wmdabutton
buttontextwww.apheresis.org/page/covid
buttonlinkhttps://apheresis.org/page/covid
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titleWMDA Foundation

WMDA

Click here for the COVID-19 vaccination guidelines developed by the Donor Medical Suitability Working Group.

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titleWMDA registries

Czech National Marrow Donors Registry (ION-5440) 

CNMDR has adopted following preliminary policy for donors after vaccination against COVID:

  • mRNA vaccines (Pfizer / BioNTech, Moderna) and protein vaccines (Novavax, Sanofi) – deferral of 7 days after each vaccination dose, provided no relevant side effects occurs.
  • Vector vaccines (Astra Zeneca, Johnson & Johnson) – deferral of of 28 days after each vaccination dose (a change of opinion after gaining more experience with vaccination cannot be ruled out).
  • Information about the donor's vaccination sent to the transplant center

With increasing experience the policy is likely to be modified.

Germany ZKRD (ION-6939)

Germany does currently not have any specific regulation as far as SARS-CoV-2 vaccination and stem cell donation is concerned. The decision if a donor is eligible for PBSC donation after (any) vaccination is generally made by the collection center's physician. They will consider European (https://www.ecdc.europa.eu/en/publicationsdata/coronavirus-disease-2019-covid-19-and-supply-substances-human-origin) and WMDA (https://share.wmda.info/display/DMSR/Vaccination) recommendations in addition to German national guidelines, but decisions are made individually.

Israel Ezer Mizion Registry Israel  Bone Marrow Donor Registry (ION-4987)

Italian Bone Marrow Registry (7450)

IBMDR according to the Italian national requirements, applies this policy for  COVID-19 Vaccination for Donors:

Deferral period after COVID-19 vaccination

  • Donors (selected for TC/Work up and donation) and  vaccinated with a vaccin based on weakened/ attenuated form of Sars -COV 2  -> deferral period of ( at least) 4 weeks after each vaccin injection
  • Donors selected for PBSC or Bone Marrow donation and vaccinated with a vaccin based on mRNA or protein subunits, with no alive virus  - > deferral period of (at least) 21 days after injection of the vaccin. This timing refers to the interval between vaccination and start of G-CSF or general anaesthetic for BM donation.
  • Donors selected for lymphocyte donation (DLI) and vaccinated with a vaccin based on mRNA or protein subunits, with no alive virus  - > deferral period of 3 -7 days (3 days minimum, 7 days recommended) after injection of the vaccin
COVID-19 vaccination after HPC or MNC donation:
  • It is recommended to document a fully recovery of the donor's blood values after the collectionbefore  planning the vaccination.

Singapore Bone Marrow Donor Programme (ION-3785)

BMDP guideline for COVID-19 Vaccination for Donors

Types of Donation

New Guidelines from WMDA –

Non Viral vector vaccines

BM collection

Collect no less than 3 days, and where possible 7 days, after vaccination.


PBSC collection

Commence G-CSF no less than 3 days, and where possible 7 days, after vaccination.


DLI

Collect no less than 3 days, and where possible 7 days, after vaccination.

Post donation vaccination

After the donor has fully recovered from the donation.

Vaccines based on a virus vector: where available, an alternative vaccine should be used due to the theoretical risk of immune interaction with G-CSF

Switzerland Swiss Registry for Blood Stem Cell Donors (ION-9341)

Deferral period after COVID-19 vaccination:

  • For Swiss donors, the deferral period after COVID-19 vaccination is 7-14 days (7 days minimum, 14 days recommended). This timing refers to the interval between vaccination and start of G-CSF or general anaesthetic for BM donation. In Switzerland, only mRNA based vaccines are administered.

COVID-19 vaccination after HPC or MNC donation:

  • A delay of at least 7 days is recommended after the collection until a planned vaccination.

United Kingdom

United States of America NMDP-Be the Match (ION-3553)

While we are providing guidelines for the timing of vaccination as it relates to collection and filgrastim administration, any donor who wants or is required to be vaccinated should receive the vaccine when it is available to them. 

  • For collection: If possible, the donor should receive the vaccination more than 72 hours before the proposed collection date.    
  • For filgrastim administration: If possible, the donor should receive the vaccination more than 72 hours before the proposed start of filgrastim to distinguish between possible side effects of the vaccine and filgrastim itself (aches and pains, headaches, etc.).

Read the full notification here.

Starting Sept. 30, 2021, we are requiring that National Marrow Donor Program® (NMDP)/Be The Match® couriers be fully vaccinated for COVID-19. This includes volunteers, staff and third-party couriers.

We are instituting this requirement to comply with the proof of vaccination upon entry required at clinical facilities at which products may be picked up or delivered. In addition, as a healthcare organization we have an obligation to the safety of our Network partners, patients, donors, NMDP/Be The Match staff and volunteers.

What the vaccination requirement means for couriers

Fully vaccinated is defined as:

  • two weeks or more after receiving a second dose in a 2-dose COVID-19 series, or
  • two weeks or more after receiving a single-dose COVID-19 vaccine (Johnson and Johnson/Janssen).

Couriers must be prepared to show proof of vaccination at any time during the courier trip. Examples of vaccination proof include:

  • Complete COVID-19 vaccination card
  • A clear image of the vaccination card on a phone
  • COVID-19 vaccination record on a mobile app
  • Digital COVID-19 vaccination QR code

Note: Some states may require vaccination cards, so couriers should plan to check local requirements in advance.

Network partners who provide couriers for NMDP/Be The Match transports are expected to be compliant with this courier vaccination requirement. There will be no exceptions. We understand some couriers may not yet be fully vaccinated and ask they refrain from accepting trips until they have done so. This is consistent with our commitment to our patients, donors and each other, and will ensure avoidance of being turned away. Please disseminate this information to the appropriate leaders and staff in your organization as necessary.

If you have any questions, please contact your Case Manager.

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titleOther organisations

EBMT

Read here COVID vaccines document with the results from various vaccines that are currently in use in Europe.