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Table of Contents

4.1 - Start

...

search 

A POST to the searches The startSearch endpoint is used to submit a search request to the Search & Match Service.  This call returns a searchId for of the search. 

Post

searches

Expand
titleRequest...
FieldDetails
Send
startSearch
Request
wmdaId*integer
example: 123456
nullable: false
matchEngine*integer
nullable: false

Unique identifier of match engine used in the search. Allowed: 2 (HAP-E), 3 (ATLAS).

Enum:
Array [ 2 ]
searchType*string
example: DREnum:
Array [ 2 ]
overallMismatchesinteger
default: 0Enum:
Array [ 8 ]
lociToBeConsidered[...]
isCbuAbLowDrb1HighResolutionboolean
default: false
nullable: true
Expand
titleResponse
FieldDetails
searchIdinteger
nullable: false
minimum: 1

4.2 - Search summary

The retrieveSearchResultssummary A GET to the searches/{searchId} endpoint is used to request a search summary for of a search. It also contains the status of a the search and can therefore be used to check whether a the search is done. 

Request:  Response:  which
Get
searches/{searchId}
Expand
titleRequest
FieldDetails
Send
retrieveSearchResultssummary
searchId*

integer

Unique identifier of the search. Can be determined by retrieving the patient search summary

Expand
titleResponse
FieldDetails
patient{...}
searchId*integer
nullable: false
minimum: 1
searchType*stringEnum:
Array [ 1 ]
matchEngine*integer
nullable: false

Unique identifier of match engine used in the search. Allowed: 2 (HAP-E), 3 (ATLAS).

Enum:
Array [ 2 ]
overallMismatches*integer
default: 0Enum:
Array [ 8 ]
status*string
nullable: falseEnum:
Array [ 3 ]
summary*{...}
inexplicable*integer
nullable: true

Total number of donors

whose phenotype cannot be explained by known haplotype

statistics*{...}
error*{...}
nullable: true
lociToBeConsidered[...]
lastUpdatedstring($date-time)
nullable: false
maxLength: 255

needed to help determine when the patient can be automatically moved to STP state

4.3 -

...

Retrieve all searches for a patient

A GET to the searches/patientSearches/{wmdaId} The retrieveSearchResultsDonors endpoint is used to retrieve search results for donors. Pagination is possible and optional filters can be provided. an overview off all searches that have been performed for a specific patient.

  • searchId

Request: 

Send
retrieveSearchResultsDonors
pagination{...}
searchId*integer
nullable: false
minimum: 1
filters{...}
sortBystring
nullable: true
default: standardEnum:
Array [ 2 ]

Response:

paging*
limit*integer
default: 100
minimum: 0
offset*integer
default: 0
minimum: 0
example: 0
totalCount*integer
minimum: 0
example: 2
searchResults*

[
minItems: 0

id*integer
nullable: false
example: 5176donorRegistryIonGetsearches/patientSearches/{wmdaId}
Expand
titleRequest
FieldDetails
wmdaId*

integer

wmdaId of patient you want to find search information for. This is NOT the patientId, but the wmdaId you received in the response body after creating your patient.

Expand
titleResponse
FieldDetails
searchId*integer
nullable: false
minimum: 1
matchEngine
*integer
nullable: false

minimum: 1000
maximum: 9999
example: 1234abbreviation*string
example: NL-WMDA
maxLength: 24

Unique identifier of match engine used in the search. Allowed: 2 (HAP-E), 3 (ATLAS).

Enum:
Array [ 2 ]
searchType*stringEnum:
Array [ 1 ]
overallMismatches*integer
default: 0Enum:
Array [ 8 ]
haplotypeFrequencySetId*integer
nullable: true
minimum: 0
example: 15
status*string
nullable: falseEnum:
[ AV, TU, RS 
Array [ 3 ]
sex
summary*
string
nullable: trueEnum:
[ M, F ]ethnicity*string
{...}
lociToBeConsidered*[...]
lastUpdated*string($date-time)
nullable: 
trueEnum:
[ UK, AF, AS, CA, HI, AFNA, AFSS, ASSW, ASSO, ASCE, ASSE, ASNE, ASOC, CAEU, CAER, CANA, CAAU, HICA, HISA, MX, OT ]idm*antiCmvStatusstring
nullable: trueEnum:
Array [ 7 ]antiCmvDatestring($date)
false
maxLength: 255

needed to help determine when the patient can be automatically moved to STP state

inexplicableinteger
nullable: true

Total number of donors whose phenotype cannot be explained by known haplotype

statistics{...}
error{...}

nullable: true

4.4 - Search results - Donors

A POST to the searches/searchResults/donors endpoint is used to retrieve search results with adult donors. Pagination is possible and optional filters can be provided. If only interested in recent changes to the search results, this can be achieved using a filter on "recordLastUpdatedFrom" field.

rhesus*
Post
searches/searchResults/donors
Expand
titleRequest
FieldDetails
pagination{...}
searchId*integer
nullable: false
minimum: 1
filters{...}
sortBy
maxLength: 10

date of CMV NAT test

cmvNatStatusstring
nullable: trueEnum:
Array [ 2 ]
cmvNatDatestring($date)
nullable: true
maxLength: 10

date of CMV NAT test

abo*string
nullable: trueEnum:
[ A, B, O, AB ]

string
nullable: true

EnumregistryAccreditationStatus*string
nullable: true


default:


[ P, N ]

 standard
Enum:
Array [ 

accredited, qualified

2 ]

firstAccreditationYear*
Expand
number
minimum: 1990
maximum: 2100
nullable: true
example: 2019matchClass*string
example: 9/10
nullable: falsenmdpGrade*string
maxLength: 5
example: MPPMP
nullable: true

A - high-res match on ARD, P - probable match, M - sure Mismatch

zeroMismatchProbability*integer
minimum: 0
maximum: 100
nullable: trueoneMismatchProbability*integer
nullable: true
minimum: 0
maximum: 100twoMismatchProbability
titleResponse
FieldDetails
paging*{...}
searchResults*[...]

4.5 - Search results - CBUs

A POST to the searches/searchResults/cbus retrieveSearchResultsDonors endpoint is used to retrieve search results with cord blood units. Pagination is possible and optional filters can be provided. If only interested in recent changes to the search results, this can be achieved using a filter on "recordLastUpdatedFrom" field.

true
maximum: 100integer0minimum0
maximum: 100integerminimum
maximum: 100integer0minimum0
maximum: 100

}]

Post
searches/searchResults/cbus
Expand
titleRequest
FieldDetails
pagination{...}
searchId*integer
nullable: 
aLocusMatchProbability*
false
minimum: 
1
filters{...}
sortBystring

nullable: true
default: 
bLocusMatchProbability*
standardEnum:
Array [ 2 ]
threeFourMismatchSortBystring

nullable: true
cLocusMatchProbability*
default: 
resolutionScoreEnum:
Array [ 3 ]
secondarySortBystring

nullable: true
default: 
drLocusMatchProbability*integer
nullable: true
minimum: 0
maximum: 100
dqLocusMatchProbability*integer
nullable: true
minimum: 0
maximum: 100
inexplicable*boolean
matchingInformationDpb1*
dpb1MatchGrade*string
nullable: trueEnum:
[ P, A, G, H, X ]
tceDigest*
permissiveProbability*integer
nullable: true
minimum: 0
maximum: 100

Probability of permissive MM. Probabilities calculated with allele frequencies for DPB1, no linkage disequilibrium taken into account

nonPermissiveHostVsGraftProbability*integer
nullable: true
minimum: 0
maximum: 100

Probability for non-permissive MM in HvG direction. Probabilities calculated with allele frequencies for DPB1, no linkage disequilibrium taken into account

nonPermissiveGraftVsHostProbability*integer
nullable: true
minimum: 0
maximum: 100

Probability for Nnon-permissive MM in GvH direction. Probabilities calculated with allele frequencies for DPB1, no linkage disequilibrium taken into account

notDeterminedProbability*integer
nullable: true
minimum: 0
maximum: 100

Probability for Not Determinable permissiveness. Probabilities calculated with allele frequencies for DPB1, no linkage disequilibrium taken into account

mismatches*
locus*string
nullable: true

locus where the mismatch is

Enum:
[ A, B, C, DRB1, DQB1, DPB1, DPA1, DQA1, DRB2, DRB3, DRB4, DRB5 ]
position*integer
nullable: true

position of the mismatch (chromosome 1 or 2)

Enum:
[ 1, 2 ]
type*string
nullable: true

type of mismatch

Enum:
[ ANTIGEN, ALLELE ]
searchResultRecordState*string
nullable: false
default: ExistingEnum:
[ Existing, New, Updated, Deleted ]
searchResultRecordStateUpdatedAt*string($date-time)
nullable: true
maxLength: 255

date and time when the last change was registered in the system

isSelected*boolean
nullable: true

true when this record has been marked as a selected

resolutionScore*number
minimum: 0
maximum: 100
nullable: true
example: 54
resolutionString*string
minLength: 5
maxLength: 5
example: AP-A-
nullable: true

A - high-res P - low or intermediate, - no typing

grid*string
nullable: true
maxLength: 19
minLength: 19
example: 9991012070433202000
donorId*string
nullable: true
example: ABC1234
maxLength: 25
donorType*string
nullable: falseEnum:
[ D, B ]
lastContactDate*string($date)
nullable: true
minLength: 10
maxLength: 10
marrowDonationsCount*integer
nullable: true
example: 0
pbscDonationsCount*integer
nullable: true
example: 1
dateOfBirth*string($date)
nullable: true
maxLength: 10
example: 1961-05-27
hla*
a*
field1*string
maxLength: 20
example: 01:01
field2*string
nullable: true
maxLength: 20
example: 02:01
b*
field1*string
maxLength: 20
example: 01:01
field2*string
nullable: true
maxLength: 20
example: 02:01
c*
field1*string
maxLength: 20
example: 01:01
field2*string
nullable: true
maxLength: 20
example: 02:01
dpa1*
field1*string
maxLength: 20
example: 01:01
field2*string
nullable: true
maxLength: 20
example: 02:01
dpb1*
field1*string
maxLength: 20
example: 01:01
field2*string
nullable: true
maxLength: 20
example: 02:01
dqa1*
field1*string
maxLength: 20
example: 01:01
field2*string
nullable: true
maxLength: 20
example: 02:01
dqb1*
field1*string
maxLength: 20
example: 01:01
field2*string
nullable: true
maxLength: 20
example: 02:01
drb1*
field1*string
maxLength: 20
example: 01:01
field2*string
nullable: true
maxLength: 20
example: 02:01
drb3*
field1*string
maxLength: 20
example: 01:01
field2*string
nullable: true
maxLength: 20
example: 02:01
drb4*
field1*string
maxLength: 20
example: 01:01
field2*string
nullable: true
maxLength: 20
example: 02:01
drb5*
field1*string
maxLength: 20
example: 01:01
field2*string
nullable: true
maxLength: 20
example: 02:01

4.4 - Full report - Donors

The retrieveFullReportDonors endpoint is used to retrieve all available information for a specific donor in a search result. 

...

  • searchResultsId

4.5 - Search results - CBUs

The retrieveSearchResultsDonors endpoint is used to retrieve search results for cord blood units. Pagination is possible and optional filters can be provided. 

...

  • searchId

4.6 - Full report - CBUs

The retrieveFullReportCBUs endpoint is used to retrieve all available information for a specific CBU in a search result. 

...

  • searchResultsId

...

tncCountEnum:
Array [ 2 ]
Expand
titleResponse
FieldDetails
paging*{...}
searchResults*[...]

4.6 - Mark selected donor

A POST to the searches/selected/donors endpoint is used to select a donor. This endpoint can be used to highlight a donor of interest.

Post
searches/selected/donors
Expand
titleRequest
FieldDetails
wmdaId

integer

wmdaId of patient you want to find search information for. This is NOT the patientId, but the wmdaId you received in the response body after creating your patient.

gridstring
nullable: true
maxLength: 19
minLength: 19
example: 9991012070433202000
setAsSelected

boolean
nullable: false

set (true) or unset (false) the indicated grid or cordId as a selected stem cell source for this patient

Expand
titleResponse
N/A

4.7 - Mark selected CBU

A POST to the searches/selected/cbus endpoint is used to select a donor. This endpoint can be used to highlight a CBU of interest.

Post
searches/selected/cbus
Expand
titleRequest
FieldDetails
wmdaId

integer

wmdaId of patient you want to find search information for. This is NOT the patientId, but the wmdaId you received in the response body after creating your patient.

cordId

string
nullable: true
maxLength: 25
example: 9991012070433202000

cordId of the CBU.

donorRegistryIoninteger
nullable: false
minimum: 1000
maximum: 9999
example: 1234
setAsSelected

boolean
nullable: false

set (true) or unset (false) the indicated grid or cordId as a selected stem cell source for this patient

Expand
titleResponse
N/A

4.8 - Get list of registries that appear in search results

A GET to the searches/{searchId}/searchResults/registries endpoint is used to retrieve an overview off all the registries that appear in the search results of a specific donor search.

Get
searches/{searchId}/searchResults/registries
Expand
titleRequest
FieldDetails
searchId*

integer

Unique identifier of the search. Can be determined by retrieving the patient search summary

Expand
titleResponse
FieldDetails
registries*

{...}

Array of unique registry IONs with their abbreviation and name

4.9 - Get list of cord blood banks that appear in search results

A GET to the searches/{searchId}/searchResults/cbbs endpoint is used to retrieve an overview off all the registries that appear in the search results of a specific donor search.

Get
searches/{searchId}/searchResults/cbbs
Expand
titleRequest
FieldDetails
searchId*

integer

Unique identifier of the search. Can be determined by retrieving the patient search summary

Expand
titleResponse
FieldDetails
cbbs*

{...}

Array of unique cbbs bank manufacterer IDs with their abbreviation and name

4.10 - Full report - Donors

A GET to the searches/donors/{searchResultsId} endpoint retrieves all available information of a specific donor in a search result. 

Get
searches/donors/{searchResultsId}
Expand
titleRequest
FieldDetails
searchResultsId*

integer

Unique identifier of the donor within a search result. This is the "id" field within searchResult

Expand
titleResponse
FieldDetails
searchIdinteger
nullable: false
minimum: 1
searchTypestring
Enum:
Array [ 1 ]
matchDurationinteger
minimum: 0
nullable: true
example: 30

time in seconds that the search took to run on the matching engine

patient{...}
search{...}
donor{...}

4.11 - Full report - CBUs

A GET to the searches/cbus/{searchResultsId} endpoint retrieves all available information of a specific CBU in a search result. 

Get
searches/cbus/{searchResultsId}
Expand
titleRequest
Field

Details

searchResultsId*

integer

Unique identifier of the search.  Can be determined by retrieving the patient search summary

Expand
titleResponse
FieldDetails
searchIdinteger
nullable: false
minimum: 1
searchTypestringEnum:
Array [ 1 ]
matchDurationinteger
minimum: 0
nullable: true
example: 30

time in seconds that the search took to run on the matching engine

search{...}
patient{...}
cbu{...}

4.12 - Refresh all searches for a patient

A POST to the searches/refreshAllPatientSearches endpoint is used to restart all searches for this patient and retrieve the new results.

Post

searches/refreshAllPatientSearches

Expand
titleRequest...
FieldDetails
wmdaId*integer
example: 123456
nullable: false
Expand
titleResponse
N/A

4.13 - Restart a single search

A POST to the searches/searchResultsRefresh endpoint is used to restart all searches for this patient and retrieve the new results.

Post

searches/searchResultsRefresh

Expand
titleRequest...
FieldDetails
searchId*integer
example: 123456
nullable: false
Expand
titleResponse
FieldDetails
newSearchIdinteger
example: 123457
nullable: false

4.14 - Suggested use of API endpoints

Below is a diagram indicated indicating the suggested use of some of the API endpoints. More API endpoints are available and the API implementer may choose to implement the endpoints in another order. Image Removed

PlantUML Macro
titleSuggested use of API endpoints
@startuml
<style>
diamond {
    BackgroundColor #ccf
  }
</style>

#palegreen:repeat:request token from 'https://login.microsoftonline.com/{tenantId}/oauth2/token';
repeat while (Valid bearer token from the Patient and Search API?) is (no)
->yes;
#palegreen:create patient: POST /patients;
#lightblue:HTTP201 created: Response body contains 'wmdaId' for this patient;
#palegreen:Start search for patient using wmdaId POST to /searches;
#lightblue:repeat:HTTP201 created: Response body contains 'searchId' for this patient;
#palegreen:repeat:Check search status: GET to /searches/{wmdaId};
backward: running;
repeat while (What is the 'status' in the response body?)
:completed;
split
#gold:Donor;
#AntiqueWhite:Retrieve search results: POST to /searches/searchResults/donors;
#pink:Pick one or more donors;
#AntiqueWhite:Use 'id' field for that donor to perform GET to
 /searches/donors/{searchResultsId} to get full report for this donor;
split again
#gold:CBU;
#AntiqueWhite:Retrieve search results: POST to /searches/searchResults/cbus;
#pink:Pick one or more CBUs;
#AntiqueWhite:Use 'id' field for that donor to perform GET to 
/searches/cbus/{searchResultsId} to get full report for this CBU;
split again
#gold:ADCU;
#AntiqueWhite:Retrieve search results: POST to /searches/searchResults/adcus;
#pink:Pick one or more ADCUs;
#AntiqueWhite:Use 'id' field for that donor to perform GET to
 /searches/adcus/{searchResultsId} to get full report for this ADCU;
endsplit
split
#palegreen:Refresh all searches for a patient: POST to /searches/refreshAllPatientSearches;
split again
#palegreen:Refresh single search: POST to /searches/searchResultsRefresh;

@enduml