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With the last release of our the Search & Match Service, the WMDA  introduces has maintained a new similar haplotype frequency set configuration to better serve all patients and provide increased accuracy when matching donors and cord blood units to patientsas was used in Optimatch (Search & Match v1). The Search & Match Service currently contains no ethnicity information for donors and therefore the new frequency sets will be calculated and based upon geographical and available data of the donors of an organisation. These frequency sets utilize high resolution typing results from organisations to extrapolate the haplotypes of the region or organisation. Thus, an organisation or geographical region must meet a minimum threshold of number of donors and availability of high resolution typing to build usable and valuable frequencies. For cord blood units. we will use the same sets that were determined in the donor populations.

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