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Czech National Marrow Donors Registry (ION-5440) 

CNMDR has adopted following preliminary policy for donors after vaccination against COVID:

  • mRNA vaccines (Pfizer / BioNTech, Moderna) and protein vaccines (Novavax, Sanofi) – deferral of 7 days after each vaccination dose, provided no relevant side effects occurs.
  • Vector vaccines (Astra Zeneca, Johnson & Johnson) – deferral of of 28 days after each vaccination dose (a change of opinion after gaining more experience with vaccination cannot be ruled out).
  • Information about the donor's vaccination sent to the transplant center

With increasing experience the policy is likely to be modified.

Italian Bone Marrow Registry (7450)

In Italy IBMDR according to national requirements, stated by CNS  - the national competent authority for blood, HSC and blood componet donations,  we have just implemented this policy:

  • Donors (selected for TC/Work up and donation) and  vaccinated with a vaccin based on weakened/ attenuated form of Sars -COV 2  -> deferral period of ( at least) 4 weeks after each vaccin injection
  • Donors (selected for TC/Work up and donation) and  vaccinated with a vaccin based on mRNA or protein subunits, with no alive virus  - > deferral period of ( at least) 48 hours after each vaccin injection
  • Donors (selected for TC/Work up and donation) and  vaccinated with a vaccin based on mRNA or protein subunits, with no alive virus but with  symptomes after the vaccination - > deferral period of ( at least) 1 week  after full recovery
  •  Donors (selected for TC/Work up and donation) and  with no sufficient information on the type of used vaccin   -> deferral period of ( at least) 4 weeks after each vaccin injection

Singapore Bone Marrow Donor Programme (ION-3785)

For both donor and patient safety, BMDP sets the following guidelines for donor receiving COVID-19 vaccination:

  • For BM and DLI collection: Donor should receive the vaccination at least 7 days before the planned collection date.
  • For PBSC collection: Donors should receive the vaccination at least 7 days before the planned start of GCSF.

SBSC, Swiss Registry for Blood Stem Cell Donors

Eligibility criteria / deferral periods after vaccination for SARS-CoV-2:

  1. After vaccination with a weakened virus vaccine ( e.g. a viral vector based vaccine or live attenuated vaccine), donors will be deferred from donation for 4 weeks
  2. Asymptomatic donors who have been vaccinated with an inactivated virus vaccine or a vaccine that does not contain any active viral component ( i.e. mRNA, DNA or recombinant protein/subunit vaccines) will be deferred from donation for 48 hours
  3. Any donor who develops symptoms after administration of any SARS-CoV-2 vaccine will be deferred from donation until 7 days after complete remission of the symptoms
  4. A deferral period of 4 weeks after vaccination applies in cases where no reliable information on the vaccine is forthcoming or available.
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