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Initiated in 1992 as a European Union Project in the 3rd Framework Programme "Advanced Informatics in Medicine (AIM)", the European Marrow Donor Information System (EMDIS) has become the standard platform for computer-based registry communication today.

The aim of EMDIS is to establish a single virtual international donor registry allowing search coordinators to get the same information and services on international donors as accurately, timely and easily as from their own national donors. The scope of operation covers all aspects of an unrelated donor search from the preliminary search to the donor workup. Technically, EMDIS defines an open specification of a protocol for the electronic communication among registries. Therefore, EMDIS is implemented as an asynchronous peer-to-peer network connecting distributed, heterogeneous databases. Membership of EMDIS is free of charge. The community provides documentation, status information, software tools, support and a project management platform.

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