Back complaints are common and need to be considered on a case-by-case basis at both recruitment and CT/work-up stages.
General guidance for adult volunteer donor (NA for maternal donor (cord blood donation))
In general, donors undergoing a bone marrow collection run the risk of exacerbating pre-existing mechanical back conditions due to the shearing forces applied to the lower back and pelvis during the procedure. However, many such donors may donate by PBSC.
Donors with non-mechanical inflammatory back conditions, particularly those associated with autoimmune disease, such as ankylosing spondylitis, should not donate by either route.
Common subgroups of back complaints are given separate guidance below:
- Mild, occasional episodes related to exertion (incl sciatica). Minimal impact on activities of daily living and occasional use of medication
- Severe chronic back pain. Impacts on activities of daily living.
- History of current or past herniated intevertebral disc
- History of back surgery
- History of fracture, dislocation or instability