Condition
Disease of the vasculature of the brain. This includes:
Stroke, or cerebrovascular accident, whether haemorrhagic or embolic
Transient ischaemic attack
Intracerebral haemorrhage, including subarachnoid, subdural and extradural bleeds
Guidance at RECRUITMENT
UNACCEPTABLE
Guidance at CT/WORK-UP
UNACCEPTABLE, PERMANENT DEFERRAL
Individual at Risk
Donor
Justification for guidance
Both embolic stroke and intracerebral haemorrhage have been reported as adverse events in stem cell donors. In order to reduce this risk, it is prudent to defer any donor with a history of cerebrovascular disease or accident.
References
Halter J, Kodera Y, Ispizua AU, Greinix HT, Schmitz N, Favre G, et al. Severe events in donors after allogeneic hematopoietic stem cell donation. Haematologica 2009;94(1):94-101.