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titleWhat is the difference between setting filters and heading/on-screen filters within the search results report?

Setting the filters in the 'Search Settings' on the Search results page prompts a new search request with those parameters. These filters will also not influence the number of results you will retrieve and will be saved in your search results.

The heading/ on-screen filters on the match results table will filter and reduce the results list that is already available. Donors and cords will retain their row number from the original list without any on-screen filters applied. The on-screen filters will not be saved to your search results and when you leave the search results page the on-screen filters will no longer be there when you come back.

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titleAre changes to the search report settings reset by the system?

Only changes applied from the search setting box will be saved to your search results. Any other on-screen filters or flags won't be saved and are reset by the system when you leave the search results page.

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titleIt seems like the search results are automatically ordered on age for adults and TNC for cords. Is that correct?

The default sorting criteria from Hap-E Search and ATLAS for donors are: 

1. HLA

2. probability in 10% intervals

3. donor age in 5 year intervals for adults


The default sorting criteria from Hap-E Search and ATLAS for cords are: 

1. HLA (6/6, 5/6, 4/6 categories)

2. Number of total nucleated cells (TNC) for cords within HLA match category

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titleWhat are the DBP1 TC3 evaluvation conditions

DPB1 TCE3 evaluation is performed only for A-B-DR(B1) typed donors under the following conditions: 

  • Patient DPB1 values must be present. Typing ambiguities in the form of multiple alleles codes, G-codes, etc. are allowed.
  • Donor DPB1 values must be present. Typing ambiguities in the form of multiple alleles codes, G-codes, etc. are allowed.
  • The donor must be in the group of potential "9/10" and "10/10" identical donors. Therefore, it is implicitly assumed that a 5-locus search report is retrieved and can be accessed. In case of a 4- or 3-locus search reports or deactivation of the grouping by allele differences, there will be no TCE3 grading.

As part of the DPB1 TC3 grading filter, you can filter the results by the following options: Matched, Permissive, Non-permissive in HvG direction, Non-permissive in GvH direction, Ambiguous, Unknown.

Although the DPB1 TC3 filter is available for cords, the results haven't been validated so it shouldn't be used.


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