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Hap-E search | ATLAS search |
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All probabilities are rounded to integer values. → 0%: - Values 0 < p < 0.5
- No shared genotype between donor and patient.
| All probabilities are rounded to integer values. → 0%: - Values 0 < p < 0.5
- No shared genotype between donor and patient.
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8.1 Locus match probabilities
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: Definition
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| ATLAS search |
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match, i.e. 10/10, 8/8 or 6/6- The locus match probability is the relative probability that this locus is a match in the 1 mismatch case.
mismatch, i.e. 9/10, 7/8 or 5/6- The locus match probability is the relative probability that this locus is a match in the 2 mismatch case.
So this probability provides information on which locus the next mismatch will occur. | match, i.e. 10/10, 8/8 or 6/6- The locus match probability is the probability that this locus is a match no matter the amount of overall mismatches.
mismatch, i.e. 9/10, 7/8 or 5/6- The locus match probability is the probability that this locus is a match no matter the amount of overall mismatches.
So this probability provides information on the probability that this locus will be a match.. |
8.2 Locus match probabilities in Hap-E search: Not displayed
In some cases the value is not defined and no locus match probability is displayed:
Hap-E search | ATLAS search |
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match- When p1 = 0 (division by zero, not defined).
mismatch- When p2 = 0 (division by zero, not defined).
- When a donor/CBU already has at least two known mismatches. As Hap-E only calculates match probabilities for up to 2 mismatches, Hap-E also is not able to calculate the locus-specific match probabilities in case of the third mismatch.
inexplicable donors - When a donor's phenotype cannot be explained by the haplotype frequency sets used for probabilistic matching. It is therefore impossible to calculate match probabilities both at the considered loci in total and per-locus.
| match- When p1 = 0 (division by zero, not defined).
mismatch- When p2 = 0 (division by zero, not defined).
- When a donor/CBU already has at least two known mismatches. As Hap-E only calculates match probabilities for up to 2 mismatches, Hap-E also is not able to calculate the locus-specific match probabilities in case of the third mismatch.
inexplicable donors
- When a donor's phenotype cannot be explained by the haplotype frequency sets used for probabilistic matching. It is therefore impossible to calculate match probabilities both at the considered loci in total and per-locus.
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8.3 Locus match probabilities in Hap-E search: Example 1
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