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WMDA StandardTitle and link to documentExplanationStatus
1.03Global Trends Report of WMDAAnnual publication presenting the unrelated stem cell donor activity on a global scale

3.13

4.09

Unrelated hematopoietic stem cell donors as research subjects

Bone Marrow Transplantation (2011), 46: 10-13

Discuss various implications of research participation of unrelated stem cell donors in research protocols.Current (2017)
10.13

Donor and liability of donor registries, donor centres and collection centres-recommendations

Bone Marrow Transplantation (2004), 33: 467-470

The paper outlines the ethical aspects of liability of involved parties and the need for insurance coverage. The article has shortcoming with the respect to legal advices.

Under review (2017), for more details:

Annette Rasche

5.04.1

Global Registration Identifier for Donors (GRID) of Hematopoietic Stem Cells: Road to Automation and Safety

Transfusion Medicine and Hemotherapy (2017), 44: 407-413

An educational paper to explain why GRID is implemented on a global scale.Current (2018)
5.04.1GRID: Moving to Unique Donor IdentifierA public webpage with educational materials to implement GRID in a registryCurrent (2018)

2.11

2.11.1

WMDA Quality ManualA template quality manual for organisations that prepare for WMDA Qualification/AccreditationCurrent (2017)
Related donors

Family donor care management: principles and recommendations

Bone Marrow Transplantation (2010) 45: 1269-1273

This document hopes to encourage increased collaboration between those caring for related and unrelated donors, and build on the extensive work, which has already been undertaken in this field to homogenize care.Current (2017)
Related donors

Related hematopoietic cell donor care: is there a role for unrelated donor registries?

Bone Marrow Transplantation (2015) 50: 637-641
Paper outlining ways how to enhance and homogenise related donor care and if registries can play a role in counselling related donors and collecting their hematopoietic stem cells.Current (2018)
1.07Criteria for Evaluation of Transplant Centres

Develop criteria and a form to evaluate TCs in the following situations:

  • TC is located in a country without a registry
  • TC is not evaluated by the local registry, or current evaluation is not appropriate
  • TC is not affiliated with a WMDA qualified or accredited organisation

TC does not need to evaluated if the following apply:

  • TC is accredited by FACT-JACIE
  • TC is affiliated with a WMDA qualified or accredited organisation
Under development
1.06Donor centre AuditCreate guidelines and checklists to audit donor centresUnder development

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WMDA StandardTitle and link to documentExplanationStatus

A gift for life (paper edition)This is the first print of the WMDA Handbook for registries; it has been replaced by an online editionOut of date

A gift for life (paper edition, Spanish translation)This is the first print of the WMDA Handbook for registries; it has been replaced by an online English editionOut of date

3.04, 3.05, 3.06, 3.09, 3.10.1, 3.3.04, 3.05, 3.06, 3.09, 3.10.1, 3.11, 3.11.1, 3.13, 3.15

Informed consent--suggested procedures for informed consent for unrelated haematopoietic stem cell donors at various stages of recruitment, donor evaluation, and donor workup.

Bone Marrow Transplantation (2003) 31: 539-545

This is a checklist to set up an informed consent at the various stages. The paper has been replaced by the WMDA Guidance to explain the WMDA Standards. The guidance can be found at: https://share.wmda.info/x/0wB7CwOut of date


Standards, regulations  and accreditation for registries involved in the worldwide exchange of hematopoietic stem cell donors and products.

Bone Marrow Transplantation (2010), 45:819-824

WMDA has developed online documentation to explain the accreditation process, which is available at WMDA Share under the pillar: 'Ensuring Quality'Out of date

International exchange of cord blood units; the registry aspects

Bone Marrow Transplantation (2010), 45: 825-831

Replaced by chapter 6 of the WMDA handbook: a gift of lifeOut of date
8.05

Concerns about the use of biosimilar granulocyte colony-stimulating factors for the mobilisation of stem cells in normal donors: position of World Marrow Donor Association.

Haematologica (2011): 96:942-943

The aim of this paper is to review the basis of regulatory approval of the biosimilar G-CSF agents, including the available safety data, with reference to the indication for mobilization of PBSC in normal donors and to make recommendations based on these.

The recommendation has been updated in 2017.

Out of date

3.22

3.22.2

A review of the genetic and long-term effects of G-CSF injections in healthy donors: a reassuring lack of evidence for the development of haematological malignancies

Bone Marrow Transplantation (2015) 50: 334-340

This paper is an update from the statement issued by WMDA in 2007. On the basis of an assessment of a continuing lack of evidence for an increased risk of malignancy in donors receiving G-CSF, the WMDA has re-issued a more reassuring statement.

The recommendation has been updated in 2017.

Out of date

3.22

3.22.2

Haematopoietic stem cell donor registries: World Marrow Donor Association recommendations for evaluation of donor health.

Bone Marrow Transplantation (2008) 42: 9-14

This document describes criteria for permanent or temporary deferral, guidelines for risk evaluation of infectious disease, examples of conditions requiring assessment and questionnaires designed to elicit relevant information about a donor's medical history and general health.

The paper has been updated in 2014.

Out of date

World Marrow Donor Association: international standards for unrelated hematopoietic stem cell donor registries

Bone Marrow Transplantation (2004) 34: 103-110

A paper describing the first publication of the WMDA Standards, the current version of the WMDA Standards is visible at: https://www.wmda.info/professionals/quality-and-accreditation/wmda-standards/Out of date

Overview of registries, HLA typing and diversity, and search algorithms

Tissue Antigens (2007) 69: 3-5

This paper is to inventorize the registries HLA typing methods and quality control used to evaluate the accuracy of typing results.Out of date
5.02

World Marrow Donor Association guidelines for use of HLA nomenclature and its validation in the data exchange among hematopoietic stem cell donor registries and cord blood banks.

Bone Marrow Transplantation (2007) 39:737-741
This paper is updated in 2012, find here the link to the updated publication: https://www.nature.com/articles/bmt201393Out of date

HLA dictionary 2004: summary of HLA-A, -B, -C, -DRB1/3/4/5, -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR, and -DQ antigens.

International Journal of Immunogenetics (2005) 32:19-69

The paper provides information on the serological equivalents of DNA typings. The paper has been updated in 2009. It is recommended to visit the IMGT/HLA website for the most recent information.Out of date

The HLA Dictionary 2001: a summary of HLA‐A, ‐B, ‐C, ‐DRB1/3/4/5 and ‐DQB1 alleles and their association with serologically defined HLA‐A, ‐B, ‐C, ‐DR and ‐DQ antigens

European Journal of Immunogenetics (2001) 28: 565-596

The paper provides information on the serological equivalents of DNA typings. The paper has been updated in 2004. It is recommended to visit the IMGT/HLA website for the most recent information.



The HLA dictionary 1999: a summary of HLA-A, -B, -C, -DRB1/3/4/5, -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR, and -DQ antigens.

Human Immunology (1999) 11: 1157-1181

The paper provides information on the serological equivalents of DNA typings. The paper has been updated in 2001. It is recommended to visit the IMGT/HLA website for the most recent information.Out of date

The search for HLA-matched donors: a summary of HLA-A*, -B*, -DRB1/3/4/5* alleles and their association with serologically defined HLA-A, -B, -DR antigens.

Tissue Antigens (1997) 50: 401-418

The paper provides information on the serological equivalents of DNA typings. The paper has been updated in 2001. It is recommended to visit the IMGT/HLA website for the most recent information.Out of date

A special report: suggested procedures for international unrelated donor search from the donor registries and quality assurance working groups of the World Marrow Donor Association (WMDA).

Bone Marrow Transplantation (2004) 34: 97-101

This paper described the procedures and responsibilities of the search for international unrelated donors. The paper has been replaced by the WMDA Handbook: A gift for life.Out of date

Haematopoietic Stem Cell Registries: WMDA definitions of a donor center This paper has been replaced by the paper: "Qualifications and training of adult stem cell donor recruiters"Out of date

Donor work-up and transport of bone marrow--recommendations and requirements for a standardized practice throughout the world from the Donor Registries and Quality Assurance Working Groups of the World Marrow Donor Association (WMDA).

Bone Marrow Transplantation (1997) 20: 621629

One of the first WMDA publications describing donor work-up.Out of date

A special report: bone marrow transplants using volunteer donors-- recommendations and requirements for a standardized practice throughout the world--1994 update. The WMDA Executive Committee

Blood (1994) 84: 2833-2389

This paper amplifies the previous publication and gives special attention to accreditation of national “hubs” (defined as coordinating centers for each country) and donor, harvest, and transplant centers, details of the marrow harvest procedure, use of peripheral blood (PB) stem cells for allografting, and use of PB lymphoid cells for treatment of leukemia relapsing after BMT.

Historical document where the WMDA Standards are presented.

Out of date

Bone marrow transplants using volunteer donors--recommendations and requirements for a standardized practice throughout the world. The Executive Committee of the World Marrow Donor Association.

Bone Marrow Transplantation (1992) 10: 287-291

Historical paper of WMDA, the first publication, outlining the hub concept.Out of date




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