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Donor
Guidance at RECRUITMENT
Establish cause, and if not otherwise excluded may join.Not acceptable
Guidance at CT/WORK-UP
Establish cause, and if not otherwise excluded may donate by PBSC only. Inform requesting transplant centre that donor is PBSC only.
Hormone replacement therapy for post-menopausal females is usually not derived from human tissues, and therefore acceptable in this context.Accept for PBSC donation, if no cardiorespiratory abnormalities
Justification for guidance
Shearing stresses applied to the pelvis and lower spine during bone marrow harvest may be a particular risk in donors with osteoporosis.
References
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