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Abbreviation / column | Description |
HLA patient | In the grey bar, you can find the HLA of your patient. This header will move with you when you are looking at results more below. |
Probability of mismatches 0, 1, 2 | Probability of a mismatch at 0 loci, 1 locus, and 2 loci. The percentages are only shown when you are using the haplotype frequency algorithm and are based on the match type you have been chosen (out of 6 then 6 loci are considered; out of 10 then 10 loci are considered). The five squares above the probability percentages are representing, respectively, locus A, B, C, DRB1, and DQB1. They are showing in letter/colour codes if a certain loci of a donor/cord is likely to match with your patient or not.
NOTE: When you are using for cords the match type ≥4/6 (at HLA-A, B, DRB1), Class I matched at antigen level and Class II matched at allele level, the probabilities are calculated based on allele level match for all loci and not only for DRB1. |
DPB1 TCE3 grading model | Various studies have shown a potential beneficial effect if the HLA‐DPB1 classification based on T‐Cell Epitopes (TCE) is considered in donor selection. Among the 9/10 and 10/10 donor candidates, those with a permissive DPB1 constellation are preferred over those showing a non‐permissive DPB1 constellation. The implementation in OptiMatch is called "DPB1 TCE3 grading" and is based on the following publications and uses the new score based algorithm that was realised with 3 TCE groups [3].
DPB1 TCE3 evaluation is performed and displayed for
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Age | Age of donor/cord |
Gender | Sex: M = male, F = female |
Blood group | Blood group, e.g. A+ = blood group A, rhesus positive, B- = blood group B, rhesus negative |
CMV | CMV status Possible values: As seen in the second entry, a value for the CMV status is not required to be entered. |
Probability of match per locus | If you expand the donor/ cord details, the probability of a match per locus becomes visible: This also correspondents with the letter/colour code from the five squares in the column probability of mismatches. These probabilities are only calculated for the 5 loci A, B, C, DRB1, and DQB1. |
GRID | GRID, Global Registration Identifier for Donors, is a |
Ethnicity | Ethnic group: The system uses the same ethnic groups as defined for the EMDIS system: |
Status | Status of a donor or CBU. For donors, the status can be available (AV), reserved for a patient (RS), temporarily unavailable (TU) |
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