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titleHow do I perform a search for mismatched donors?

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titleIs it possible to perform a search for mismatched donors during the initial search?

No, at this moment you can only perform a zero mismatch donor and/or ≥8/10 cords search. You will only be able to view/request mismatched donors/CBUs when...

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titleWhat is the difference between Allele and Haplotype frequencies?

Allele frequencies give the proportions of individual alleles. Haplotype frequencies give the proportions of specific haplotypes i.e. several alleles in phase and therefore preserve linkage information.

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titleWhat Haplotype Frequencies will be used for the probability matching?
The Search & Match Service uses a Global Frequency set determined from the comprehensive donor fileWMDA has calculated and applied many specific haplotype frequency sets to the Search & Match Service. Read more on the following page.
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titleCan I switch off the Predictive Search and run it just like the old system?
 You can switch to use allele frequencies instead of haplotype frequencies, which is the matching approach/method that the old system used. However, all matching algorithms vary slightly so the new search powered by Hap-E Search and/or ATLAS may not match results from the old system, even with allele frequencies in use.
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titleHow can I request a Search Advise for a Patient?

If you are experiencing difficulties in your selection of a donor/cord for your patient, you can request a search advice from the WMDA HLA experts. To request an advise, go to your patient list, click on the patient ID and at the bottom of the Update patient form you will find a button with 'Request Search Advisory'. An email message will then open with the patient information and some additional fields with requirements. Please fill out as much as possible and send the email. You will receive the advice also by email.

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