...

The Search & Match Service performs probability matching by using either a haplotype frequency or allele frequency algorithm. Please the Hap-E Search algorithm.  There is a difference in the meaning of the indicated probabilities per locus between Optimas and Hap-E. For more info on this please see the following slides and video.  Please keep in mind that probability matching will just calculate chances and you should use it as a tool in combination with your own knowledge of HLA. Do not select donors/cords solely on the probabilities calculated by the system. You can read more about haplotype frequencies here. 

Getting started

Accessing the Search & Match Service

...

There is a difference in the meaning of the indicated probabilities per locus between Optimas and Hap-E. For more info on this please see the following slides and video. 

Links to assist you in your searches

...