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- Filter for returning only donors/cord blood with typing at C (and/or DQB1). Available today.
- Filter on match class - a search coordinator can go directly to the 5/8 or 4/8 potential matches. Scheduled for delivery December 2022.
- "Score" based sorting for three and/or four mismatch cord blood results (find details below). Scheduled for delivery December 2022.
- Match probability calculation for three and/or four mismatches (find details below). Scheduled for delivery Q1 2023.
"Score" based sorting
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for three and/or four mismatch cord blood results (see option 3 in above paragraph) - temporary solution
In general it is true that the more highly typed a CBU/ donor on a match list is, the higher the probability of a match. As we are currently not able to provide match probabilities and it will take a few months to fully develop, we will use a score based approach. This works in the following way
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Below you can find some examples.
Match probability calculation for three and/or four mismatches (see in paragraph above option 4) -
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long-term solution
Calculation of actual match probabilities would provide a better way of ranking than score-based ranking. Unfortunately this requires quite a lot of work in core elements of the Hap-E algorithm. This therefore needs to be done with great care and needs to be thoroughly tested in order to make sure no part of the Hap-E algorithm is accidentally broken as a result of the added functionality. It therefore cannot be delivered until Q1 of 2023.
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