...
Why are locus-specific match probabilities not available for Hap-E searches?
Because of the different definitions between match probabilities calculated by ATLAS and Hap-E and the nature of how match probabilities are displayed by Hap-E, it is not possible to display locus-specific match probabilities for p0, p1 and p2.
...
For additional information about the definition of the match probabilities in Hap-E, please visit this page.
For ATLAS search results
...
- The match probability for p0 is defined as the match probability for a full match at a specific locus in case of 0 mismatches
- The match probability for p1 is defined as the mismatch probability for a single mismatch at a specific locus in case of 1 mismatches
- The match probability for p2 is defined as the mismatch probability for two mismatches at a specific locus in case of 2 mismatches
In the example below, the probabilities for a full match (no mismatches) for HLA-B and -DRB1 are 100%. For HLA-A and HLA-C, the matching probabilities are 98% and 1%, respectively.
Therefore, the match probabilities displayed for p0 are considered match probabilities.
The probability for a single mismatch at HLA-B and -DRB1 are is 0%. For HLA-A and HLA-C, the probabilities for a single mismatch are 2% and 97%, respectively.
Therefore, the match probabilities displayed for p1 and p2 are considered mismatch probabilities.
...