3 and 4 mismatch searches have now been implemented for Cord searches. Here are some things you need to know:
- In order to minimise unnecessary use of resource-intensive 3 and 4 mismatch cord searches, you first need to have finished
- a 2 mismatch search before you can start a 3 mismatch search
- a 3 mismatch search before you can start a 4 mismatch search
- a 3 mismatch search before you can start a 4 mismatch search
- a 2 mismatch search before you can start a 3 mismatch search
- Just like in the legacy system, no overal match probabilities are calculated and sorting is performed within the match class (i.e. 5/8. 4/8) based on the TNC count or CD34 count (depending on what you have selected. TNC count is the default)
- It is advisable to use filters as the number of results can be great. You can for example filter on the minimum TNC, minimum CD34 or by certain registries or mismatch locations.